Luis Rosero Bixby
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Item Interethnic differences in the accuracy of anthropometric indicators of obesity in screening for high risk of coronary heart disease(International Journal of Obesity, 33(5), 2009) Herrea, VM.; Casas, Juan P.; Miranda, JJ.; Perel, P.; Pichardo, R.; González, A.; Sánchez, José R.; Ferreccio, Catterina.; Aguilera, X.; Silva, E.; Oróstegui, Myriam; Gómez, LF.; Chirinos, JA.; Lezama, Medina J.; Pérez, Cynthia M.; Suárez, E.; Ortiz. AP.; Rosero Bixby, Luis; Schapochnik, Noberto; Ortiz, Zulma; Ferrante, Daniel; Diaz, M.; Bautista, LE.Obesity is a recognized risk factor for the development of cardiovascular diseases and for allcause mortality among ethnic groups in the United States.1,2 Also among Latin Americans, that is, Hispanics living in their country of origin, obesity doubles the risk of coronary heart disease (CHD)3 and seems to contribute to an excess of 18 to 49% in the risk of coronary events.4 In view of the large impact of obesity on cardiovascular risk, anthropometric indicators of obesity are commonly used as a tool to identify individuals and populations at high risk of cardiovascular events. Body mass index (BMI) is a measure of overall obesity, whereas waist circumference (WC) and waist-to-hip ratio (WHR) are used as indicators of abdominal obesity. Although these obesity indicators have been independently associated with CHD incidence and mortality in different populations,5-7 several investigators and public health organizations have recently questioned whether cut points derived from Whites from Europe and the United States are appropriate for use in other populations.8-10 For instance, the World Health Organization (WHO) has recently suggested lowering BMI action cut points to 23 and 27.5 kg/m2 for Asians, 8 and the International Diabetes Federation’s guidelines for assessing metabolic syndrome recommends the use of South Asian’s WC cut points for Latin Americans and makes no recommendation for cut points among Blacks from the United States.11 In this study we used data from six Latin-American countries and from the United States National Health and Nutrition Examination Survey (NHANES) to compare the accuracy of BMI, WC and WHR, that is, their ability to correctly classify individuals as having a high or a low risk of CHD.Item The Latin American Consortium of Studies in Obesity (LASO)(Obesity Reviews, vol.10(3), 2009) Bautista Lorenzo, Leonelo Enrique; Casas, Juan P.; Herrera Galindo, Víctor Mauricio; Miranda Montero, Jaime J.; Perel, Pablo; Pichardo Estevez, Rafael; González, Angel; Sánchez, José R.; Ferreccio, Catterina; Aguilera Sanhueza, Ximena; Silva, Eglé; Oróstegui, Myriam; Gómez Gutiérrez, Luis Fernando; Chirinos Medina, Julio A.; Medina Lezama, Josefina; Pérez, Cynthia M.; Suárez, Erick; Ortiz Martínez, Ana Patricia; Rosero Bixby, Luis; Schapochnik, Noberto; Ortiz, Zulma; Ferrante, DanielCurrent, high-quality data are needed to evaluate the health impact of the epidemic of obesity in Latin America. The Latin American Consortium of Studies of Obesity (LASO) has been established, with the objectives of (i) Accurately estimating the prevalence of obesity and its distribution by sociodemographic characteristics; (ii) Identifying ethnic, socioeconomic and behavioural determinants of obesity; (iii) Estimating the association between various anthropometric indicators or obesity and major cardiovascular risk factors and (iv) Quantifying the validity of standard definitions of the various indexes of obesity in Latin American population. To achieve these objectives, LASO makes use of individual data from existing studies. To date, the LASO consortium includes data from 11 studies from eight countries (Argentina, Chile, Colombia, Costa Rica, Dominican Republic, Peru, Puerto Rico and Venezuela), including a total of 32 462 subjects. This article describes the overall organization of LASO, the individual studies involved and the overall strategy for data analysis. LASO will foster the development of collaborative obesity research among Latin American investigators. More important, results from LASO will be instrumental to inform health policies aiming to curtail the epidemic of obesity in the region.