Luis Rosero Bixby
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Item Confirmación histológica del diagnóstico de cáncer cérvico uterino en Costa Rica 1982-84(Acta Médica Costarricense, Vol. 33; No, 3, 1990) Oberle, Mark W.; Rosero Bixby, Luis; Saeed, MekbelUn panel de patólogos costarricenses efectuó un análisis histológico de las biopsias de 677 casos de cáncer de cuello de útero in situ e invasor diagnosticados en Costa Rica en 1982 - 1984. El panel confirmó el diagnóstico inicial del 81% de los casos de cáncer in situ y del 72% de los casos de cáncer invasor. El panel redigo la severidad del diagnóstico a displasia u otra lesión no cancerosa en el 12% de los casos de cáncer in situ y en el 3% de los casos de cáncer invasor. El 8% de los casos de cáncer invasor fueron reclasificados como in situ. Un 9% adicional podrían ser reclasificados en el mismo sentido, pero hay dudas sobre el diagnóstico definitivo. El error más grave ocurrió en 3% de los casos Inicialmente diagnosticados como de cáncer in situ los cuales fueron reclasificados por el panel como cáncer invasor, pero este error probablemente no afectó el tratamiento de las pacientes. Las modificaciones en el diagnóstico obtenidos en el presente estudio pueden derivarse de un examen más cuidadoso efectuado por el panel o de la dificultad propia del diagnóstico histológico del cáncer de cuello de útero.Item Contraceptive use and fertility in Costa Rica, 1986(International Family Planning Perspectives, Vol. 14, No. 3, (September 1988), 1988) Oberle, Mark W.; Sosa Jara, Doris; Madrigal Pana, Johnny; Becker, Stan; Rosero Bixby, LuisContraceptive prevalence in Costa Rica is higher than almost anywhere else in Latin America, with 70 percent of currently married women using a contraceptive method. Differentials in contraceptive use by educational level and between urban and rural areas are actually quite small compared with those in other Latin American countries. While levels of contraceptive use among married women 20-44 years of age remained relatively stable between 1976 and 1986, total fertility rates increased slightly over that period, perhaps because of changing fertility intentions or changing patterns of contraceptive use. For example, Costa Rican women have increased their reliance on barrier methods and decreased use of the pill. The majority of women who were not practicing contraception were either pregnant or breastfeeding an infant; only about one in five nonusers could be considered candidates for contraceptive use. One-fifth of all 15-19-year-old women and two-fifths of all 20-24-year-olds had had premarital intercourse. Most young adults who had had premarital intercourse did not practice contraception at first intercourse.Item Sexual behavior, sexually transmitted diseases, and risk of cervical cancer(Epidemiology, Vol. 6, No. 4, 1995) Stone, Katherine M.; Zaidi, Akbar; Rosero Bixby, Luis; Oberle, Mark W.; Reynolds, Gladys; Larsen, Sandra A.; Nahmias, Andre J.; Lee, Francis K.; Schachter, Juluis; Guinan, Mary E.o explore sexually transmitted diseases and sexual behavior as risk factors for cervical cancer, we analyzed data from a population-based case-control study of breast and cervical cancer in Costa Rica. Data from 415 cases of cervical carcinoma in situ, 149 cases of invasive cervical cancer, and 764 controls were included in the analysis. Multivariate analysis showed that lifetime number of sex partners, first intercourse before age 15 years, number of livebirths, herpes simplex virus type 2 seropositivity, and serologic evidence of previous chlamydial in? fection were predictors of carcinoma in situ. Serologic evidence of previous syphilis was not associated with carcinoma in situ. Predictors for invasive cervical cancer included lifetime num? ber of sex partners, first intercourse before age 15 years, number of livebirths, serologic evidence of previous syphilis, herpes simplex type 2 infection, and chlamydial infection. Cigarette smoking, socioeconomic status, self-reprted history of sexually transmitted diseases, and douching were not associated with either carcinoma in situ or invasive cervical cancer. (Epidemiology 1995;6:409-414)